An update on Dendritic Cell-Based Cancer Immunotherapy
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چکیده
Abbreviations: APC: Antigen-Presenting Cell; DCs: Dendritic Cells; RECIST: Response Evaluation Criteria in Solid Tumors; HLA: Human Leukocyte Antigen; MDSCs: Myeloid-Derived Suppressor Cells; CTLs: Cytotoxic T Cells; GM-CSF: Granulocyte-Macrophage ColonyStimulating Factor; TGF: Transforming Growth Factor; IL: Interleukin ; VEGF: Vascular Endothelial Growth Factor; PGE2: Prostaglandin E2; PD-L1: Programmed Death-Ligand 1; FDA: Food and Drug Administration; WT1: Wilms’ Tumor 1; MUC1: Mucin 1 Cell Surface Associated; HER2: Human Epidermal Growth Factor Receptor 2; CEA: Carcinoembryonic Antigen; PSA: Prostate-Specific Antigen; WT1-DC: DC Vaccines Primed with HLA class I/II-Restricted WT1 Peptides; ELISPOT: Enzyme-Linked Immunosorbent Spot; WT1-CTLs: WT1 Antigen-Specific Cytotoxic T Lymphocytes; IFN: Interferon; PBMCs: Peripheral Blood Mononuclear Cells; HSCT: Hematopoietic Stem Cell Transplantation; G-CSF: Granulocyte Colony-Stimulating Factor
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